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All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility

Mammalian spermatozoa become motile at ejaculation, but before they can fertilize the egg, they must acquire more thrust to penetrate the cumulus and zona pellucida. The forceful asymmetric motion of hyperactivated spermatozoa requires Ca(2+) entry into the sperm tail by an alkalinization-activated...

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Main Authors: Qi, Huayu, Moran, Magdalene M., Navarro, Betsy, Chong, Jayhong A., Krapivinsky, Grigory, Krapivinsky, Luba, Kirichok, Yuriy, Ramsey, I. Scott, Quill, Timothy A., Clapham, David E.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770895/
https://ncbi.nlm.nih.gov/pubmed/17227845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610286104
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