The role of Hv1 and CatSper channels in sperm activation

Elevations of sperm intracellular pH and Ca(2+) regulate sperm motility, chemotaxis, capacitation and the acrosome reaction, and play a vital role in the ability of the sperm cell to reach and fertilise the egg. In human spermatozoa, the flagellar voltage-gated proton channel Hv1 is the main H(+) ex...

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Bibliographic Details
Main Authors: Lishko, Polina V, Kirichok, Yuriy
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2010
Subjects:
Special Section Reviews: Voltage and Ion Sensing Channels: Three Views of the Same Tale
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010136/
https://ncbi.nlm.nih.gov/pubmed/20679352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.194142
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