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Disruption of the principal, progesterone-activated sperm Ca(2+) channel in a CatSper2-deficient infertile patient
The female steroid hormone progesterone regulates ovulation and supports pregnancy, but also controls human sperm function within the female reproductive tract. Progesterone causes elevation of sperm intracellular Ca(2+) leading to sperm hyperactivation, acrosome reaction, and perhaps chemotaxis tow...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637729/ https://ncbi.nlm.nih.gov/pubmed/23530196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216588110 |
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