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LKB1, the multitasking tumour suppressor kinase
Mutations in the lkb1 gene are found in Peutz-Jeghers syndrome (PJS), with loss of heterozygosity or somatic mutations at the lkb1 locus, suggesting the gene product, the serine/threonine kinase LKB1, may function as a tumour suppressor. Patients with PJS are at a greater risk of developing cancers...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Copyright 2005 Journal of Clinical Pathology
2005
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1770539/ https://ncbi.nlm.nih.gov/pubmed/15623475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2003.015255 |
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