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LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressor

Lung cancer is featured with high mortality, with a 15% five-year survival rate worldwide. Genetic alterations, such as loss of function of tumor suppressor genes, frequently contribute to lung cancer initiation, progression and metastasis. Liver kinase B1 (LKB1), as a serine/threonine kinase and tu...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Gao, Yijun, Ge, Gaoxiang, Ji, Hongbin
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875258/
https://ncbi.nlm.nih.gov/pubmed/21380642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1021-6
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