Tumor Suppressor Serine/Threonine Kinase LKB1 Expression, Not Kinase Activity, Increased in the Vascular Smooth Muscle Cells and Neointima in the Rat Carotid Artery Injury Model

BACKGROUND AND OBJECTIVES: Vascular smooth muscle cell (VSMC) proliferation is responsible for the restenosis of previously inserted coronary stents. Angiotensin II (Ang II) is known to regulate VSMC proliferation. LKB1, a serine/threonine kinase, interacts with the p53 pathway and acts as a tumor s...

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Autori principali: Jeong, Jin-Ok, Kim, Jeong-Hee, Ahn, Kye-Taek, Park, Hyung Seo, Jang, Won Il, Park, Jae-Hyeong, Lee, Jae-Hwan, Choi, Si Wan, Kim, Jin Man, Seong, In-Whan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Cardiology 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008825/
https://ncbi.nlm.nih.gov/pubmed/21217931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4070/kcj.2010.40.11.552
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