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HpaII methyltransferase is mutagenic in Escherichia coli.

A genetic reversion assay to study C-to-T mutations within CG sites in DNA is described. It was used to demonstrate that the presence of HpaII methyltransferase (MTase) in Escherichia coli causes a substantial increase in C-to-T mutations at CG sites. This is similar to the known mutagenic effects o...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Bandaru, B, Wyszynski, M, Bhagwat, A S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7751315/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.10.2950-2952.1995
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