The role of cholesterol and sphingolipids in chemokine receptor function and HIV-1 envelope glycoprotein-mediated fusion

BACKGROUND: HIV-1 entry into cells is a multifaceted process involving target cell CD4 and the chemokine receptors, CXCR4 or CCR5. The lipid composition of the host cell plays a significant role in the HIV fusion process as it orchestrates the appropriate disposition of CD4 and co-receptors required...

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Bibliografiske detaljer
Main Authors: Ablan, Sherimay, Rawat, Satinder S, Viard, Mathias, Wang, Ji Ming, Puri, Anu, Blumenthal, Robert
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769366/
https://ncbi.nlm.nih.gov/pubmed/17187670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-3-104
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