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Photoinduced Reactivity of the HIV-1 Envelope Glycoprotein with a Membrane-Embedded Probe Reveals Insertion of Portions of the HIV-1 Gp41 Cytoplasmic Tail into the Viral Membrane

The interactions of HIV-1 Env (gp120-gp41) with CD4 and coreceptors trigger a barrage of conformational changes in Env that drive the membrane fusion process. Various regions of gp41 have profound effects on HIV entry and budding. However, the precise interactions between gp41 and the membrane have...

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Autors principals: Viard, Mathias, Ablan, Sherimay D., Zhou, Ming, Veenstra, Timothy D., Freed, Eric O., Raviv, Yossef, Blumenthal, Robert
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583176/
https://ncbi.nlm.nih.gov/pubmed/18198900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701920f
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