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Restricted lateral mobility of plasma membrane CD4 impairs HIV-1 envelope glycoprotein mediated fusion

We investigated the effect of receptor mobility on HIV-1 envelope glycoprotein (Env)-triggered fusion using B16 mouse melanoma cells that are engineered to express CD4 and CXCR4 or CCR5. These engineered cells are resistant to fusion mediated CD4-dependent HIV-1 envelope glycoprotein. Receptor mobil...

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Bibliografiske detaljer
Main Authors: RAWAT, SATINDER S., ZIMMERMAN, CHRISTINA, JOHNSON, BENITRA T., CHO, EDWARD, LOCKETT, STEPHEN J., BLUMENTHAL, ROBERT, PURI, ANU
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466082/
https://ncbi.nlm.nih.gov/pubmed/18097956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09687680701613713
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