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Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell
We present evidence that variations in cyclin D1 levels through the cell cycle are essential for continuing proliferation. Cyclin D1 levels must be high during G1 phase for a cell to initiate DNA synthesis, but then must be suppressed to low levels during S phase to allow for efficient DNA synthesis...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1769361/ https://ncbi.nlm.nih.gov/pubmed/17176475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-32 |
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