Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels

BACKGROUND: The expression level of cyclin D1 plays a vital role in the control of proliferation. This protein is reported to be degraded following phosphorylation by glycogen synthase kinase 3 (GSK3) on Thr-286. We recently showed that phosphorylation of Thr-286 is responsible for a decline in cycl...

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Autori principali: Yang, Ke, Guo, Yang, Stacey, William C, Harwalkar, Jyoti, Fretthold, Jonathan, Hitomi, Masahiro, Stacey, Dennis W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592484/
https://ncbi.nlm.nih.gov/pubmed/16942622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-7-33
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