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The energetic network of hotspot residues between Cdc25B phosphatase and its protein substrate
We have investigated the functional network of hotspot residues at the remote docking site of two cell cycle regulators, namely Cdc25B phosphatase and its native protein substrate Cdk2-pTpY/CycA. Specifically, we have studied the roles of energetically important residues (Arg488, Arg492, Tyr497 on C...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1769329/ https://ncbi.nlm.nih.gov/pubmed/16950393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.07.090 |
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