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Structural insights into RNA quality control: The Ro autoantigen binds misfolded RNAs via its central cavity
The Ro 60 kDa autoantigen is a major target of the immune response in patients with systemic lupus erythematosus. In vertebrate cells, Ro binds misfolded small RNAs and likely functions in RNA quality control. In eukaryotes and bacteria, Ro also associates with small RNAs called Y RNAs. We present s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1769319/ https://ncbi.nlm.nih.gov/pubmed/15907467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.03.009 |
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