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A misfolded form of 5S rRNA is complexed with the Ro and La autoantigens.

In both vertebrate and invertebrate cells, the 60-kDa Ro autoantigen is bound to small cytoplasmic RNAs known as Y RNAs. In Xenopus oocytes, the 60-kDa Ro protein is also complexed with a class of 5S rRNA precursors that contain internal mutations. Because these 5S rRNA precursors are processed inef...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shi, H, O'Brien, C A, Van Horn, D J, Wolin, S L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369414/
https://ncbi.nlm.nih.gov/pubmed/8752087
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