Using SEC-RPLC and RPLC-CIEF as two-dimensional separation strategies for protein profiling

Bottom-up proteomics (analyzing peptides that result from protein digestion) has demonstrated capability for broad proteome coverage and good throughput. However, due to incomplete sequence coverage, this approach is not ideally suited to the study of modified proteins. The modification complement o...

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Main Authors: Simpson, David C., Ahn, Seonghee, Pasa-Tolic, Ljiljana, Bogdanov, Bogdan, Mottaz, Heather M., Vilkov, Andrey N., Anderson, Gordon A., Lipton, Mary S., Smith, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769308/
https://ncbi.nlm.nih.gov/pubmed/16732621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.200600037
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