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Facilitating the Hyphenation of CIEF and MALDI-MS for Two-Dimensional Separation of Proteins

Both CIEF and MALDI-MS are frequently used in protein analysis, but hyphenation of the two is not investigated proportionally. One of the major reasons is that the additives (such as carrier ampholytes and detergent) in CIEF severely suppress the MALDI-MS signal, which hampers the hyphenation of the...

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Detalhes bibliográficos
Main Authors: Cheng, Chang, Lu, Joann J., Wang, Xiayan, Roberts, Jonathan, Liu, Shaorong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025491/
https://ncbi.nlm.nih.gov/pubmed/20603827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201000085
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