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Prion infection impairs the cellular response to oxidative stress

The molecular mechanism of neurodegeneration in transmissible spongiform encephalopathies remains uncertain. In this study, it was demonstrated that prion-infected hypothalamic neuronal GT1 cells displayed a higher sensitivity to induced oxidative stress over noninfected cells. In addition, the infe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Milhavet, Ollivier, McMahon, Hilary E. M., Rachidi, Walid, Nishida, Noriyuki, Katamine, Shigeru, Mangé, Alain, Arlotto, Marie, Casanova, Danielle, Riondel, Jacqueline, Favier, Alain, Lehmann, Sylvain
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11095725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.250289197
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