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Progressive cardiac hypertrophy and dysfunction in atrial natriuretic peptide receptor (GC-A) deficient mice

Objective: To investigate how permanent inhibition of guanylyl cyclase A receptor (GC-A) affects cardiac function. Methods: Hearts of GC-A−/− and corresponding wild type mice (GC-A+/+) were characterised by histological, western blotting, and northern blotting analyses. Cardiac function was evaluate...

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Detalhes bibliográficos
Main Authors: Kuhn, M, Holtwick, R, Baba, H A, Perriard, J C, Schmitz, W, Ehler, E
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 by Heart 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1767056/
https://ncbi.nlm.nih.gov/pubmed/11907014
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