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Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice

Mice lacking natriuretic peptide receptor A (NPRA) have marked cardiac hypertrophy and chamber dilatation disproportionate to their increased blood pressure (BP), suggesting, in support of previous in vitro data, that the NPRA system moderates the cardiac response to hypertrophic stimuli. Here, we h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Knowles, Joshua W., Esposito, Giovanni, Mao, Lan, Hagaman, John R., Fox, Jennifer E., Smithies, Oliver, Rockman, Howard A., Maeda, Nobuyo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC199554/
https://ncbi.nlm.nih.gov/pubmed/11306601
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