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Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases

This paper reviews the existing evidence regarding the use of superagonistic anti-CD28 antibodies (CD28 superagonists) for therapeutic manipulation of regulatory T cells (T(reg) cells). The molecular properties of superagonistic anti-CD28 antibodies allow the generation of a strong activating signal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beyersdorf, N, Hanke, T, Kerkau, T, Hunig, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766908/
https://ncbi.nlm.nih.gov/pubmed/16239397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.042564
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