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Cloning, sequence analysis, expression, and inactivation of the Corynebacterium glutamicum icd gene encoding isocitrate dehydrogenase and biochemical characterization of the enzyme.

NADP(+)-dependent isocitrate dehydrogenase (ICD) is an important enzyme of the intermediary metabolism, as it controls the carbon flux within the citric acid cycle and supplies the cell with 2-oxoglutarate and NADPH for biosynthetic purposes. In the amino acid-producing organism Corynebacterium glut...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Eikmanns, B J, Rittmann, D, Sahm, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7836312/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.3.774-782.1995
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