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Neutralization of a single arginine residue gates open a two-pore domain, alkali-activated K(+) channel
Potassium channels share a common selectivity filter that determines the conduction characteristics of the pore. Diversity in K(+) channels is given by how they are gated open. TASK-2, TALK-1, and TALK-2 are two-pore region (2P) KCNK K(+) channels gated open by extracellular alkalinization. We have...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1766441/ https://ncbi.nlm.nih.gov/pubmed/17197424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606173104 |
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