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Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

Malignant rhabdoid tumor (MRT) is an aggressive, highly lethal cancer of young children. Tumors occur in various locations, including kidney, brain, and soft tissues. Despite intensive therapy, 80% of affected children die, often within 1 year of diagnosis. The majority of MRT samples and cell lines...

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Detalhes bibliográficos
Main Authors: Roberts, Charles W. M., Galusha, Shelly A., McMenamin, Máirín E., Fletcher, Christopher D. M., Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17655/
https://ncbi.nlm.nih.gov/pubmed/11095756
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