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cAMP activation of PKA defines an ancient signaling mechanism
cAMP and the cAMP binding domain (CBD) constitute a ubiquitous regulatory switch that translates an extracellular signal into a biological response. The CBD contains α- and β-subdomains with cAMP binding to a phosphate binding cassette (PBC) in the β-sandwich. The major receptors for cAMP in mammali...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1765484/ https://ncbi.nlm.nih.gov/pubmed/17182741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609033103 |
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