Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4(+) and CD8(+) T cell turnover in HIV-infected patients

To evaluate the effects of HIV infection on T cell turnover, we examined levels of DNA synthesis in lymph node and peripheral blood mononuclear cell subsets by using ex vivo labeling with BrdUrd. Compared with healthy controls (n = 67), HIV-infected patients (n = 57) had significant increases in the...

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Autores principales: Lempicki, Richard A., Kovacs, Joseph A., Baseler, Michael W., Adelsberger, Joseph W., Dewar, Robin L., Natarajan, Ven, Bosche, Marjorie C., Metcalf, Julia A., Stevens, Randy A., Lambert, Laurie A., Alvord, W. Gregory, Polis, Michael A., Davey, Richard T., Dimitrov, Dimiter S., Lane, H. Clifford
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC17652/
https://ncbi.nlm.nih.gov/pubmed/11095734
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