Induction of prolonged survival of CD4(+) T lymphocytes by intermittent IL-2 therapy in HIV-infected patients

HIV infection leads to decreases in the number of CD4(+) T lymphocytes and an increased risk for opportunistic infections and neoplasms. The administration of intermittent cycles of IL-2 to HIV-infected patients can lead to profound increases (often greater than 100%) in CD4 cell number and percenta...

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Hauptverfasser: Kovacs, Joseph A., Lempicki, Richard A., Sidorov, Igor A., Adelsberger, Joseph W., Sereti, Irini, Sachau, William, Kelly, Grace, Metcalf, Julia A., Davey, Richard T., Falloon, Judith, Polis, Michael A., Tavel, Jorge, Stevens, Randy, Lambert, Laurie, Hosack, Douglas A., Bosche, Marjorie, Issaq, Haleem J., Fox, Stephen D., Leitman, Susan, Baseler, Michael W., Masur, Henry, Di Mascio, Michele, Dimitrov, Dimiter S., Lane, H. Clifford
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2005
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174914/
https://ncbi.nlm.nih.gov/pubmed/16025158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23196
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