Induction of prolonged survival of CD4(+) T lymphocytes by intermittent IL-2 therapy in HIV-infected patients

HIV infection leads to decreases in the number of CD4(+) T lymphocytes and an increased risk for opportunistic infections and neoplasms. The administration of intermittent cycles of IL-2 to HIV-infected patients can lead to profound increases (often greater than 100%) in CD4 cell number and percenta...

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Detalhes bibliográficos
Main Authors: Kovacs, Joseph A., Lempicki, Richard A., Sidorov, Igor A., Adelsberger, Joseph W., Sereti, Irini, Sachau, William, Kelly, Grace, Metcalf, Julia A., Davey, Richard T., Falloon, Judith, Polis, Michael A., Tavel, Jorge, Stevens, Randy, Lambert, Laurie, Hosack, Douglas A., Bosche, Marjorie, Issaq, Haleem J., Fox, Stephen D., Leitman, Susan, Baseler, Michael W., Masur, Henry, Di Mascio, Michele, Dimitrov, Dimiter S., Lane, H. Clifford
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174914/
https://ncbi.nlm.nih.gov/pubmed/16025158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23196
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