Effect of saturable serum protein binding on the pharmacokinetics of unbound cefonicid in humans.
Previous studies have demonstrated high, concentration-dependent serum protein binding of cefonicid. To determine the in vivo pharmacokinetic significance of these observations, the pharmacokinetics of both total and unbound (non-protein-bound) cefonicid was studied in six volunteers after a single...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3789691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.565 |
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