Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?

BACKGROUND: Anti-inflammatory treatment affects ischemic damage and neurogenesis in rodent models of cerebral ischemia. We investigated the potential benefit of COX-2 inhibition with parecoxib in spontaneously hypertensive rats (SHRs) subjected to transient middle cerebral artery occlusion (tMCAo)....

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Detalhes bibliográficos
Main Authors: Kelsen, Jesper, Kjær, Katrine, Chen, Gang, Pedersen, Michael, Røhl, Lisbeth, Frøkiær, Jørgen, Nielsen, Søren, Nyengaard, Jens R, Rønn, Lars Christian B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764728/
https://ncbi.nlm.nih.gov/pubmed/17150094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-3-31
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