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AVP-Induced Increase in AQP2 and p-AQP2 Is Blunted in Heart Failure during Cardiac Remodeling and Is Associated with Decreased AT1R Abundance in Rat Kidney

AIM: The objective was to examine the renal effects of long-term increased angiotensin II and vasopressin plasma levels in early-stage heart failure (HF). We investigated the regulations of the V2 vasopressin receptor, the type 1A angiotensin II receptor, the (pro)renin receptor, and the water chann...

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Pubblicato in:PLoS One
Autori principali: Lütken, Sophie Constantin, Frøkiær, Jørgen, Nielsen, Søren
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319737/
https://ncbi.nlm.nih.gov/pubmed/25658446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116501
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