A prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria

Mitochondrial leucyl-tRNA synthetase (LeuRS) in the yeast Saccharomyces cerevisiae provides two essential functions. In addition to aminoacylation, LeuRS functions in RNA splicing. The details of how it came to act in splicing are not known. Here we show that Mycobacterium tuberculosis and human mit...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Houman, Fariba, Rho, Seung Bae, Zhang, Jiansu, Shen, Xiaoyu, Wang, Chien-Chia, Schimmel, Paul, Martinis, Susan A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11087829/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.240465597
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