Leucyl-tRNA synthetase deficiency systemically induces excessive autophagy in zebrafish

Abstract Leucyl-tRNA synthetase (LARS) is an enzyme that catalyses the ligation of leucine with leucine tRNA. LARS is also essential to sensitize the intracellular leucine concentration to the mammalian target of rapamycin complex 1 (mTORC1) activation. Biallelic mutation in the LARS gene causes inf...

全面介紹

書目詳細資料

Principais autores:	Masanori Inoue, Hiroaki Miyahara, Hiroshi Shiraishi, Nobuyuki Shimizu, Mika Tsumori, Kyoko Kiyota, Miwako Maeda, Ryohei Umeda, Tohru Ishitani, Reiko Hanada, Kenji Ihara, Toshikatsu Hanada
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2021-04-01
叢編:	Scientific Reports
在線閱讀:	https://doi.org/10.1038/s41598-021-87879-4
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!