A prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria

Mitochondrial leucyl-tRNA synthetase (LeuRS) in the yeast Saccharomyces cerevisiae provides two essential functions. In addition to aminoacylation, LeuRS functions in RNA splicing. The details of how it came to act in splicing are not known. Here we show that Mycobacterium tuberculosis and human mit...

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Detalles Bibliográficos
Main Authors: Houman, Fariba, Rho, Seung Bae, Zhang, Jiansu, Shen, Xiaoyu, Wang, Chien-Chia, Schimmel, Paul, Martinis, Susan A.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC17646/
https://ncbi.nlm.nih.gov/pubmed/11087829
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