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NFAT and NFκB Activation in T Lymphocytes: A Model of Differential Activation of Gene Expression

Mathematical models for the regulation of the Ca(2+)-dependent transcription factors NFAT and NFκB that are involved in the activation of the immune and inflammatory responses in T lymphocytes have been developed. These pathways are important targets for drugs, which act as powerful immunosuppressan...

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Detalhes bibliográficos
Main Authors: Fisher, Wayne G., Yang, Pei-Chi, Medikonduri, Ram K., Jafri, M. Saleet
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers-Plenum Publishers 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764593/
https://ncbi.nlm.nih.gov/pubmed/17031595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-006-9179-4
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