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Ca(2+) signaling in T lymphocytes: the interplay of the endoplasmic reticulum, mitochondria, membrane potential, and CRAC channels on transcription factor activation

T cell receptor stimulation initiates a cascade of reactions that cause an increase in intracellular calcium (Ca(2+)) concentration mediated through inositol 1,4,5-trisphosphate (IP(3)). To understand the basic mechanisms by which the immune response in T cells is activated, it is useful to understa...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Yang, Pei-Chi, Jafri, M. Saleet
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063158/
https://ncbi.nlm.nih.gov/pubmed/32181396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e03526
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