Intermolecular Failure of L-type Ca(2+) Channel and Ryanodine Receptor Signaling in Hypertrophy

Pressure overload–induced hypertrophy is a key step leading to heart failure. The Ca(2+)-induced Ca(2+) release (CICR) process that governs cardiac contractility is defective in hypertrophy/heart failure, but the molecular mechanisms remain elusive. To examine the intermolecular aspects of CICR duri...

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Detalhes bibliográficos
Main Authors: Xu, Ming, Zhou, Peng, Xu, Shi-Ming, Liu, Yin, Feng, Xinheng, Bai, Shu-Hua, Bai, Yan, Hao, Xue-Mei, Han, Qide, Zhang, Youyi, Wang, Shi-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764437/
https://ncbi.nlm.nih.gov/pubmed/17214508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050021
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