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TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs
We examined the molecular pharmacology and in vivo effects of a TRPV1 receptor antagonist, N-(4-Tertiarybutylphenyl)-4(3-cholorphyridin-2-yl)-tetrahydro-pyrazine1(2H) – carboxamide (BCTC) on the guinea pig TRPV1 cation channel. BCTC antagonized capsaicin-induced activation and PMA-mediated activatio...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1764418/ https://ncbi.nlm.nih.gov/pubmed/17173683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-9974-2-10 |
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