Imipenem pharmacokinetics and body fluid concentrations in patients receiving high-dose treatment for serious infections.

Serum, urine, tissue, and body fluids were collected from 40 adult patients who were receiving imipenem/cilastatin treatment for serious infections. Thirty-two patients were given 1 g every 6 h (4 g/day), and eight received 500 mg (2 g/day). Mean peak concentrations in serum were 34.9 +/- 4.0 microg...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	MacGregor, R R, Gibson, G A, Bland, J A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3459389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.2.188
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