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Imipenem pharmacokinetics and body fluid concentrations in patients receiving high-dose treatment for serious infections.

Serum, urine, tissue, and body fluids were collected from 40 adult patients who were receiving imipenem/cilastatin treatment for serious infections. Thirty-two patients were given 1 g every 6 h (4 g/day), and eight received 500 mg (2 g/day). Mean peak concentrations in serum were 34.9 +/- 4.0 microg...

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Bibliografische gegevens
Hoofdauteurs: MacGregor, R R, Gibson, G A, Bland, J A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC176375/
https://ncbi.nlm.nih.gov/pubmed/3459389
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