Cilastatin does not alter superoxide dismutase activity.

Cilastatin inhibits dehydropeptidase-I, a zinc metaloenzyme that metabolizes imipenem. Because zinc stabilizes the mammalian superoxide dismutase, we postulated that cilastatin would also inhibit the dismutase. Cilastatin concentrations at levels threefold higher than those expected in urine, howeve...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Proctor, R A, Textor, J A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3867330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.5.691
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