Cilastatin does not alter superoxide dismutase activity.

Cilastatin inhibits dehydropeptidase-I, a zinc metaloenzyme that metabolizes imipenem. Because zinc stabilizes the mammalian superoxide dismutase, we postulated that cilastatin would also inhibit the dismutase. Cilastatin concentrations at levels threefold higher than those expected in urine, howeve...

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Bibliografiska uppgifter

I publikationen:	Antimicrob Agents Chemother
Huvudupphov:	Proctor, R A, Textor, J A
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1985
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3867330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.5.691
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