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Effects of elevation of serum cholesterol and administration of amphotericin B complexed to lipoproteins on amphotericin B-induced toxicity in rabbits.

Amphotericin B was infused into normal rabbits or rabbits made hypercholesterolemic by diet. There was no difference in amphotericin B-induced toxicity between these two groups. Amphotericin B given in a mixture with human low-density lipoproteins was more toxic than when given without lipoproteins.

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Koldin, M H, Kobayashi, G S, Brajtburg, J, Medoff, G
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1985
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176327/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4037773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.1.144
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