Pharmacokinetics, Distribution in Serum Lipoproteins and Tissues, and Renal Toxicities of Amphotericin B and Amphotericin B Lipid Complex in a Hypercholesterolemic Rabbit Model: Single-Dose Studies

The purpose of this study was to determine if a relationship exists among total serum and lipoprotein cholesterol concentration, the severity of amphotericin B (AmpB)-induced renal toxicity, and the serum pharmacokinetics of AmpB in hypercholesterolemic rabbits administered AmpB and AmpB lipid compl...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Wasan, Kishor M., Kennedy, Allison L., Cassidy, Shawn M., Ramaswamy, Manisha, Holtorf, Lorilynne, Chou, Jenny Wen-Lin, Pritchard, P. Haydn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3146
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