Pharmacokinetics, Distribution in Serum Lipoproteins and Tissues, and Renal Toxicities of Amphotericin B and Amphotericin B Lipid Complex in a Hypercholesterolemic Rabbit Model: Single-Dose Studies

The purpose of this study was to determine if a relationship exists among total serum and lipoprotein cholesterol concentration, the severity of amphotericin B (AmpB)-induced renal toxicity, and the serum pharmacokinetics of AmpB in hypercholesterolemic rabbits administered AmpB and AmpB lipid compl...

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Bibliographic Details
Main Authors: Wasan, Kishor M., Kennedy, Allison L., Cassidy, Shawn M., Ramaswamy, Manisha, Holtorf, Lorilynne, Chou, Jenny Wen-Lin, Pritchard, P. Haydn
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC106014/
https://ncbi.nlm.nih.gov/pubmed/9835506
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