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IFNα/β promotes cell survival by activating NF-κB

IFNs play critical roles in host defense by modulating the expression of various genes via signal transducer and activator of transcription factors. We show that IFNα/β activates another important transcription factor, NF-κB. DNA-binding activity of NF-κB was induced by multiple type 1 IFNs and was...

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Hlavní autoři: Yang, Chuan He, Murti, Aruna, Pfeffer, Susan R., Basu, Leela, Kim, Jong G., Pfeffer, Lawrence M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC17627/
https://ncbi.nlm.nih.gov/pubmed/11095741
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