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Mice Lacking Neutrophil Elastase Are Resistant to Bleomycin-Induced Pulmonary Fibrosis

Neutrophil elastase is a serine protease stored in the azurophilic granules of leukocytes. It has been implicated in the pathology of several lung diseases and is generally presumed to contribute to the tissue destruction and extracellular matrix damage associated with these conditions. To delineate...

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Detalhes bibliográficos
Main Authors: Chua, Felix, Dunsmore, Sarah E., Clingen, Peter H., Mutsaers, Steven E., Shapiro, Steven D., Segal, Anthony W., Roes, Jürgen, Laurent, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762691/
https://ncbi.nlm.nih.gov/pubmed/17200183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060352
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