Targeting the Expression of Platelet-Derived Growth Factor Receptor by Reactive Stroma Inhibits Growth and Metastasis of Human Colon Carcinoma

The stromal cells within colon carcinoma express high levels of the platelet-derived growth factor receptor (PDGF-R), whereas colon cancer cells do not. Here, we examined whether blocking PDGF-R could inhibit colon cancer growth in vivo. KM12SM human colon cancer cells were injected subcutaneously (...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kitadai, Yasuhiko, Sasaki, Takamitsu, Kuwai, Toshio, Nakamura, Toru, Bucana, Corazon D., Fidler, Isaiah J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762464/
https://ncbi.nlm.nih.gov/pubmed/17148668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060653
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares