Dissecting Oct3/4-Regulated Gene Networks in Embryonic Stem Cells by Expression Profiling

POU transcription factor Pou5f1 (Oct3/4) is required to maintain ES cells in an undifferentiated state. Here we show that global expression profiling of Oct3/4-manipulated ES cells delineates the downstream target genes of Oct3/4. Combined with data from genome-wide chromatin-immunoprecipitation (Ch...

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Detalles Bibliográficos
Main Authors: Matoba, Ryo, Niwa, Hitoshi, Masui, Shinji, Ohtsuka, Satoshi, Carter, Mark G., Sharov, Alexei A., Ko, Minoru S.H.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762406/
https://ncbi.nlm.nih.gov/pubmed/17183653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000026
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