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Klf4 Cooperates with Oct3/4 and Sox2 To Activate the Lefty1 Core Promoter in Embryonic Stem Cells

Although the POU transcription factor Oct3/4 is pivotal in maintaining self renewal of embryonic stem (ES) cells, little is known of its molecular mechanisms. We previously reported that the N-terminal transactivation domain of Oct3/4 is required for activation of Lefty1 expression (H. Niwa, S. Masu...

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Detalhes bibliográficos
Main Authors: Nakatake, Yuhki, Fukui, Nobutaka, Iwamatsu, Yuko, Masui, Shinji, Takahashi, Kadue, Yagi, Rika, Yagi, Kiyohito, Miyazaki, Jun-ichi, Matoba, Ryo, Ko, Minoru S. H., Niwa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636862/
https://ncbi.nlm.nih.gov/pubmed/16954384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00468-06
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