Fine Tuning of Globin Gene Expression by DNA Methylation

Expression patterns in the globin gene cluster are subject to developmental regulation in vivo. While the γ(A) and γ(G) genes are expressed in fetal liver, both are silenced in adult erythrocytes. In order to decipher the role of DNA methylation in this process, we generated a YAC transgenic mouse s...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Goren, Alon, Simchen, Giora, Fibach, Eitan, Szabo, Piroska E., Tanimoto, Keiji, Chakalova, Lyubomira, Pfeifer, Gerd P., Fraser, Peter J., Engel, James D., Cedar, Howard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762317/
https://ncbi.nlm.nih.gov/pubmed/17183675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000046
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky