Fine Tuning of Globin Gene Expression by DNA Methylation

Expression patterns in the globin gene cluster are subject to developmental regulation in vivo. While the γ(A) and γ(G) genes are expressed in fetal liver, both are silenced in adult erythrocytes. In order to decipher the role of DNA methylation in this process, we generated a YAC transgenic mouse s...

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Detaylı Bibliyografya
Asıl Yazarlar: Goren, Alon, Simchen, Giora, Fibach, Eitan, Szabo, Piroska E., Tanimoto, Keiji, Chakalova, Lyubomira, Pfeifer, Gerd P., Fraser, Peter J., Engel, James D., Cedar, Howard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2006
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762317/
https://ncbi.nlm.nih.gov/pubmed/17183675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000046
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