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Fine Tuning of Globin Gene Expression by DNA Methylation
Expression patterns in the globin gene cluster are subject to developmental regulation in vivo. While the γ(A) and γ(G) genes are expressed in fetal liver, both are silenced in adult erythrocytes. In order to decipher the role of DNA methylation in this process, we generated a YAC transgenic mouse s...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1762317/ https://ncbi.nlm.nih.gov/pubmed/17183675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000046 |
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